The purpose of this study was to determine whether sali-vary cortisol sampling would be a feasible effectiveness outcome measure for a community-based RT program serving children with disabilities. The program utilized in this study provides weekly RT interventions in three 10-week cycles over an 18-month period for 62 children aged 3-21 enrolled in a local public school special edu-cation program. Salivary cortisol sampling, a biomarker for stress response, was collected via bioswab pre/post-intervention on weeks 1, 6, and 10 of each cycle. In or-der to determine feasibility, the collection rate, measur-ability, and comparability of saliva samples were tracked over the study period. The first goal of collecting 75% of the possible cryovials was not met due to an actual col-lection rate of 56%. Participant absence was found to be responsible for 62% of the uncollected cryovials. How-ever, of those collected, 95% were measurable and 77% were comparable, which met the second prediction of achieving measurable samples as a rate of 50% or bet-ter. Researchers deemed cortisol sampling as feasible as correcting collection errors, which caused 17% loss of the overall possible sample, will allow for an adequate sample size for statistical analysis in future studies.
Author Kirstin L. Whitley, Susan E. Lynch, Catherine L. Franssen, Lindsey S. Sparrock
Volume Vol. 53, No. 4 (2019)